PRODUCTS AND SERVICES

DNA origami structures

You decide wether you only want to buy the staple strands for the structure, a whole kit with all ingredients or the pre-folded structure.

We provide a broad spectrum of DNA Origami structures that have been published multiple times and have been optimised over the years.

Those standard structures vary in length, size and shape and therefore serve a variety of applications.

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Why order with us?

  • As ready as you need it

    For our Standard Structures you choose how much you want to do yourself. We provide all needed raw materials, DIY kits and completely assembled ready-to-use structures.

  • Fully tailored

    We make edits to the standard structures according to your needs. Dyes, Quencher, Linker Molecules, Antibodies, Gold-Nanoparticles and much more can be added with low effort. Reach out for your Custom Quote.

  • Fast with High Quality

    Our streamlined process enables rapid delivery of all products, with turnaround times varying by purification level. Each product undergoes rigorous quality control, ensuring consistent excellence across our entire portfolio.

From DNA Origami Experts for you

With decades of experience, our team has been at the forefront of DNA Origami innovation from its inception. We've contributed to the development of a wide range of intricate DNA structures, both for internal research and client projects. This extensive experience allows us to understand which designs offer the greatest stability, adaptability, and practical application across various fields.

To accelerate your research, our experts can meet with your team to identify how DNA Origami can best enable your research. Through a few targeted questions, we help optimize your project to meet precise experimental requirements.

Each of our raw materials and ready-to-use DNA structures undergo rigorous quality control, ensuring they meet the highest standards to support your success.

Staple Kits

You already know which structure you want to fold and have all needed materials in the lab? We offer the staple strands for several designs. You can also find the fitting Scaffolds in our ssDNA-Shop

DIY Kits

It's your first time folding an Origami or you just want all supplies needed for your structure in one Kit? We provide completed Kits (sufficient for 50 pmol structure) that come with Staple Strands, Scaffold DNA, Buffer and the Loading-Dye for your QC Gel. All you need is a Thermo Cycler.

Ready-to-use Structures

You need a quickly accessible origami you can use directly? We offer prefabricated structures in different purifications.

You can receive your Origami un-purified, free of excess (by PEG purification) staples or ultra-purified (through Gel purification).

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Frequently Asked Questions

How does DNA Origami work?

DNA origami relies on a self-assembly to form 3D nanostructures from scaffold DNA and a set of unique staple strand oligonucleotides. For a brief introduction to the technology, please visit https://www.tilibit.com/pages/technology. For an overview over the technology, please see https://www.nature.com/articles/nmeth.1570.

Are there software tools for the design of DNA Origami structures?

Cadnano is a free DNA Origami design tool. You can download the software at http://cadnano.org.

CanDo is a structure prediction software for DNA Origami objects. Design files can be analysed at http://cando.dna-origami.org

What are applications of DNA Origami structures?

For a brief overview of potential DNA origami applications, please visit https://www.tilibit.com/pages/technology. For an extensive overview of applications, see the following review article: https://pubs.acs.org/doi/abs/10.1021/acs.chemrev.6b00825.

How can I purify my DNA Origami?

Depending on the level of purity to aim to achieve there is several approaches. By PEG-Precipitation, Filtration or Gel-Purification. We happily provide you with protocols for each and when purchasing a ready-to-use structure we offer different purification levels.

How should DNA Origamis be stored?

Once assembled DNA Origamis are quite stable and can be stored at room temperature up to a week. For long term storage we recommend storing at -20°